KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECH1
All Species:
30.91
Human Site:
S108
Identified Species:
75.56
UniProt:
Q13011
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13011
NP_001389.2
328
35816
S108
D
C
R
A
V
V
I
S
G
A
G
K
M
F
T
Chimpanzee
Pan troglodytes
XP_001167817
328
35675
S108
D
C
R
A
V
V
I
S
G
A
G
K
M
F
T
Rhesus Macaque
Macaca mulatta
XP_001084167
320
35031
S100
D
C
R
A
V
V
I
S
G
A
G
K
M
F
T
Dog
Lupus familis
XP_533678
328
35870
S108
D
C
R
A
V
V
I
S
G
A
G
K
V
F
T
Cat
Felis silvestris
Mouse
Mus musculus
O35459
327
36100
S107
D
C
R
A
V
V
V
S
G
A
G
K
M
F
T
Rat
Rattus norvegicus
Q62651
327
36153
S107
D
C
R
A
V
V
V
S
G
A
G
K
M
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086341
285
31456
Q88
G
S
D
F
L
Q
Q
Q
E
D
D
P
A
R
I
Zebra Danio
Brachydanio rerio
NP_001006068
308
33755
S88
E
C
R
A
V
V
F
S
G
A
G
K
L
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608375
312
33800
S93
D
C
R
A
I
V
L
S
A
S
G
K
H
F
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784041
285
31394
P88
E
L
M
Q
G
A
I
P
G
S
T
D
L
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
92.9
79.8
N.A.
74
75.3
N.A.
N.A.
N.A.
62.2
62.5
N.A.
48.1
N.A.
N.A.
51.2
Protein Similarity:
100
99.3
95.7
88.7
N.A.
87.8
87.8
N.A.
N.A.
N.A.
73.1
75
N.A.
65.5
N.A.
N.A.
65.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
0
80
N.A.
66.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
6.6
93.3
N.A.
86.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
80
0
10
0
0
10
70
0
0
10
0
0
% A
% Cys:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
10
0
0
0
0
0
0
10
10
10
0
10
0
% D
% Glu:
20
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
0
0
80
0
% F
% Gly:
10
0
0
0
10
0
0
0
80
0
80
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
10
0
50
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% K
% Leu:
0
10
0
0
10
0
10
0
0
0
0
0
20
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
50
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
10
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
80
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
0
80
0
20
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
80
% T
% Val:
0
0
0
0
70
80
20
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _